Opportunity Information: Apply for RFA AG 22 026
The Transition to Aging Research for Predoctoral Students (F99/K00 Clinical Trial Not Allowed), listed as RFA-AG-22-026, is a National Institutes of Health (NIH) discretionary grant opportunity focused on strengthening the pipeline of researchers working in aging and geriatrics. Its central goal is to increase, retain, and diversify the pool of trainees who will build careers in aging-related research, meaning it is designed not only to bring more predoctoral researchers into the field, but also to help them stay in it and successfully transition toward independent research careers.
This funding opportunity uses the NIH F99/K00 mechanism, which is a two-phase "transition" award structure commonly intended to support a trainee near the end of doctoral training and then help bridge them into the next career stage. In practical terms, it is meant to provide structured support as a student completes their PhD research training (the F99 phase) and then moves into a subsequent mentored position (the K00 phase), with an emphasis on establishing a strong trajectory in aging and geriatric research. The notice also clearly states "Clinical Trial Not Allowed," which means applicants must propose research and training activities that do not meet NIH's definition of a clinical trial. Projects involving prospective assignment of human participants to interventions to evaluate effects on health-related outcomes would not be allowable under this announcement.
Eligibility is broad and spans many types of U.S.-based organizations. Eligible applicants include various levels of government (state, county, city or township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations that are not federally recognized tribal governments. The opportunity also allows public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education), and for-profit organizations other than small businesses, along with small businesses and other applicants as described in the listing. In addition, the announcement explicitly highlights categories of "other eligible applicants" to underscore inclusivity and encourage applications from institutions and organizations that serve historically underrepresented populations or play key community roles. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions, as well as Indian/Native American tribal governments that are not federally recognized.
At the same time, the opportunity draws firm boundaries around foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply. Non-domestic components of U.S. organizations are also not eligible, and foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In other words, the applicant organization and the supported activities must be domestic, without foreign components attached to the award.
From an administrative standpoint, the program is offered by NIH and falls under the Health funding activity category, with CFDA number 93.866. The opportunity was created on 2021-11-04 and had an original closing date of 2022-02-03. The listing does not provide an award ceiling or expected number of awards in the provided source data, which typically means prospective applicants would need to consult the full announcement text for detailed budget structure, allowable costs, and any institute-specific expectations. Overall, the program is best understood as a workforce-development investment by NIH: it aims to cultivate promising predoctoral researchers and position them to continue into aging and geriatric research careers, while emphasizing diversity and maintaining strict limits on clinical trial activity and foreign organizational involvement.Apply for RFA AG 22 026
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Transition to Aging Research for Predoctoral Students (F99/K00 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2021-11-04.
- Applicants must submit their applications by 2022-02-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Transition to Aging Research for Predoctoral Students (F99/K00, Clinical Trial Not Allowed) - RFA-AG-22-026
What is RFA-AG-22-026?
RFA-AG-22-026 is an NIH discretionary grant opportunity titled "Transition to Aging Research for Predoctoral Students (F99/K00 Clinical Trial Not Allowed)." It focuses on strengthening the pipeline of researchers working in aging and geriatrics.
What is the main purpose of this funding opportunity?
The central goal is to increase, retain, and diversify the pool of trainees who will build careers in aging-related research. It is intended to bring more predoctoral researchers into aging and geriatrics and support them as they remain in the field and move toward independent research careers.
What does the F99/K00 mechanism mean in practical terms?
The F99/K00 is a two-phase transition award designed to support a trainee near the end of doctoral training and then bridge them into the next mentored career stage. The F99 phase supports the completion of PhD research training, and the K00 phase supports a subsequent mentored position, emphasizing a strong trajectory in aging and geriatric research.
Who is this opportunity intended to support?
It is intended for predoctoral trainees (predoctoral students) near the end of their doctoral research training who are preparing to transition into the next stage of mentored research training, with a focus on aging- and geriatrics-related research careers.
Is this opportunity focused on workforce development or on a specific research topic?
Based on the provided information, it is best understood as a workforce-development investment by NIH, aimed at cultivating promising predoctoral researchers and supporting their progression into aging and geriatric research careers.
Are clinical trials allowed under this announcement?
No. The notice clearly states "Clinical Trial Not Allowed." Applicants must propose research and training activities that do not meet NIH's definition of a clinical trial.
What kinds of projects would be considered a clinical trial and therefore not allowed?
The information provided indicates that projects involving the prospective assignment of human participants to interventions to evaluate effects on health-related outcomes would not be allowable under this announcement.
Which organizations are eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Native American tribal organizations (other than federally recognized tribal governments)
- Public housing authorities/Indian housing authorities
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- For-profit organizations other than small businesses
- Small businesses
- Other applicants as described in the listing
Does the opportunity encourage applications from institutions serving underrepresented populations?
Yes. The announcement explicitly highlights "other eligible applicants" and underscores inclusivity, encouraging applications from institutions and organizations that serve historically underrepresented populations or play key community roles.
Which "other eligible applicants" are explicitly highlighted?
The provided information lists the following as explicitly highlighted categories:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Faith-based or community-based organizations
- Regional organizations
- Eligible federal agencies
- U.S. territories or possessions
- Indian/Native American tribal governments that are not federally recognized
Are foreign (non-U.S.) organizations eligible to apply?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply.
Can a U.S. organization apply if it has non-domestic components?
No. Non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed under this opportunity?
No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed.
Does this mean all supported activities must be conducted domestically?
Yes. The provided information indicates that the applicant organization and the supported activities must be domestic, without foreign components attached to the award.
Which agency offers this funding opportunity?
This opportunity is offered by the National Institutes of Health (NIH).
What is the funding activity category?
The opportunity falls under the Health funding activity category.
What is the CFDA number for this opportunity?
The CFDA number listed is 93.866.
When was this opportunity created?
The opportunity was created on 2021-11-04.
What was the original closing date?
The original closing date was 2022-02-03.
Does the provided listing include an award ceiling or the expected number of awards?
No. The provided source data does not include an award ceiling or the expected number of awards.
Where would an applicant typically find details about budget structure and allowable costs?
The provided information notes that prospective applicants would typically need to consult the full announcement text for details such as budget structure, allowable costs, and any institute-specific expectations.
What is the overall intent of the program?
Overall, the program is intended to cultivate promising predoctoral researchers in aging and geriatrics, support their retention in the field, and help them transition toward independent research careers, while maintaining strict limits on clinical trial activity and foreign organizational involvement.
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