Opportunity Information: Apply for RFA MH 20 205
The Early Psychosis Intervention Network (EPINET): Practice-Based Research to Improve Treatment Outcomes funding opportunity (RFA-MH-20-205) is a National Institutes of Health initiative, administered under the U.S. Department of Health and Human Services, that supports the creation and operation of regional scientific hubs focused on early psychosis care. The core purpose is to strengthen practice-based research in real-world clinical settings that already provide evidence-based specialty services to people in the early stages of psychotic illness. In this announcement, "early psychosis" is defined broadly as the period beginning with the onset of an affective or non-affective psychotic disorder and extending through up to five years after a first episode of psychosis (FEP). The emphasis is on producing actionable evidence that improves what clinics do day to day and, ultimately, improves patient outcomes.
The FOA is designed to fund EPINET regional scientific hubs that can function as organizing centers for research embedded within clinical care. These hubs are expected to support studies and related infrastructure that help clinics identify people earlier, make diagnoses more accurately, improve clinical assessment practices, test or refine interventions, and enhance how services are delivered. In practical terms, that means research questions can span the full pathway of care, from how individuals are recognized and referred into specialty early psychosis programs, to how treatment plans are selected and adjusted over time, to how clinics measure symptoms, functioning, recovery goals, and other health outcomes. The overall orientation is toward improving intervention effectiveness and service delivery in ways that can be implemented and sustained in routine clinical workflows.
The grant mechanism is an R01, with clinical trials listed as optional, meaning applicants may propose studies that include clinical trial components or may focus on other types of practice-based research that do not meet the definition of a clinical trial. The activity category is health, and the funding instrument is a grant. The opportunity set an award ceiling of up to $1,000,000 per award and anticipated making three awards, signaling a relatively selective competition aimed at establishing a small number of strong regional hubs capable of influencing practice across multiple clinics and systems.
Eligibility is broad and includes many types of organizations that could realistically build a regional research hub tied to clinical early psychosis services. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations (other than small businesses); small businesses; and other entities as clarified in the FOA. This wide eligibility reflects the fact that early psychosis care and research partnerships often span universities, healthcare providers, community organizations, and public systems.
Key administrative details from the source include a creation date of November 18, 2019, and an original closing date of March 10, 2020. The listing is associated with CFDA number 93.242. Put simply, the FOA backed the development of a networked, regionally organized research infrastructure embedded in specialty early psychosis clinics, with the goal of generating practical, real-world evidence to improve early identification, assessment, treatment, service delivery, and health outcomes for individuals in the first several years of psychotic illness.Apply for RFA MH 20 205
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Early Psychosis Intervention Network (EPINET): Practice-Based Research to Improve Treatment Outcomes (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on Nov 18, 2019.
- Applicants must submit their applications by Mar 10, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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