Opportunity Information: Apply for EPA G2021 ORD D1
This EPA grant opportunity, titled "Collection of Concordant Multimedia Measurements to Evaluate PFAS Human Exposure Pathways" (Funding Opportunity Number EPA G2021 ORD D1; CFDA 66.511), supports projects that add targeted environmental and exposure-related measurements to existing human cohorts where PFAS biomonitoring is already underway. The core idea is not simply to measure PFAS in people, but to collect matching, coordinated ("concordant") data from relevant media and exposure sources so researchers can interpret biomonitoring results more confidently and trace back which sources and pathways are most responsible for what shows up in the body.
The opportunity is run by the EPA's Center for Public Health and Environmental Assessment (CPHEA) in coordination with the Agency's Safe and Healthy Communities National Research Program. It is framed as a discretionary grant program focused on environmental research and public health exposure science. The intent is to strengthen PFAS exposure measurement methods and encourage studies to gather the same kinds of supporting information in comparable ways, which helps individual projects have greater impact and makes it easier to compare findings across different cohorts and locations.
The research emphasis is on "multimedia measurements," meaning measurements taken across multiple relevant environmental media and personal exposure points, rather than relying on blood or urine data alone. In practice, this could include collecting and analyzing samples or data related to potential PFAS exposure routes such as drinking water, indoor dust, air, soil, food-related pathways, consumer products, or other locally important sources. By pairing these external measurements with biomonitoring data collected from participants, the resulting dataset can help clarify how PFAS move from the environment into people, which pathways dominate under certain conditions, and why exposures differ among individuals or communities.
A key theme is standardization and comparability: the EPA is explicitly encouraging the common collection of aligned measurements and contextual information so that results from different cohorts can be interpreted together, not just in isolation. This matters for PFAS because there are many compounds, many potential sources, and multiple exposure routes that can vary substantially by geography, behaviors, infrastructure, and product use. Concordant measurement approaches can improve attribution of exposure sources, reduce uncertainty in interpreting biomonitoring concentrations, and strengthen the scientific basis for identifying the most important pathways for risk management and public health action.
Funding details indicate an award ceiling of $250,000 per award, with an expectation of two awards. The opportunity was created July 7, 2021, and originally closed August 23, 2021, with the notice indicating that applicants should consult the official announcement (including Section IV) for submission requirements, methods, and exact due dates. Eligibility is listed broadly as "Others," with the specific eligible applicant types to be clarified in the announcement's eligibility section.
In short, this grant is designed to build better PFAS exposure science by adding coordinated, real-world environmental and pathway measurements to ongoing PFAS biomonitoring cohorts, generating data that can explain where PFAS exposures are coming from and which pathways contribute most to human body burdens.Apply for EPA G2021 ORD D1
- The Environmental Protection Agency in the environment sector is offering a public funding opportunity titled "COLLECTION OF CONCORDANT MULTIMEDIA MEASUREMENTS TO EVALUATE PFAS HUMAN EXPOSURE PATHWAYS" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 66.511.
- This funding opportunity was created on Jul 07, 2021.
- Applicants must submit their applications by Aug 23, 2021 Please refer to the announcement, including Section IV, for additional information on submission methods and due dates.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the title of this EPA grant opportunity?
The opportunity is titled "Collection of Concordant Multimedia Measurements to Evaluate PFAS Human Exposure Pathways."
What is the Funding Opportunity Number (FON) and CFDA listing?
The Funding Opportunity Number is EPA G2021 ORD D1, and the CFDA number is 66.511.
What is the overall purpose of this funding opportunity?
The purpose is to support projects that add targeted environmental and exposure-related measurements to existing human cohorts where PFAS biomonitoring is already underway. The goal is to pair biomonitoring results with coordinated measurements from relevant environmental media and exposure sources so researchers can better interpret what PFAS levels in people mean and identify which sources and pathways are most responsible for those levels.
What does "concordant multimedia measurements" mean in this grant?
It refers to collecting matching, coordinated measurements across multiple relevant environmental media and exposure points (not just in people). "Concordant" emphasizes alignment and comparability in what is collected and how it is collected, so that external measurements can be meaningfully interpreted alongside PFAS biomonitoring data.
Is this grant meant to fund PFAS biomonitoring alone?
No. The core idea is not simply to measure PFAS in people, but to add supporting measurements from the environment and other exposure sources that help explain biomonitoring findings and trace exposures back to likely pathways.
What kinds of cohorts does this opportunity focus on?
It focuses on existing human cohorts where PFAS biomonitoring is already underway. The grant supports adding targeted environmental and exposure-related measurements to those ongoing efforts.
What are examples of "multimedia" samples or data that could be included?
The opportunity describes measurements across relevant environmental media and personal exposure points. Examples mentioned include drinking water, indoor dust, air, soil, food-related pathways, consumer products, and other locally important sources.
Why does EPA emphasize collecting measurements across multiple media?
Because relying on blood or urine data alone can make it difficult to identify where exposures are coming from. Coordinated measurements across multiple media can help clarify how PFAS move from the environment into people, which pathways dominate under certain conditions, and why exposures differ among individuals or communities.
What is the role of standardization and comparability in this opportunity?
A major theme is encouraging common, aligned measurements and contextual information so that results from different cohorts can be interpreted together, not just as stand-alone studies. This improves the ability to compare findings across different locations and cohorts and increases the impact of individual projects.
How can concordant measurements improve interpretation of PFAS biomonitoring results?
By pairing biomonitoring data with aligned external measurements, researchers can reduce uncertainty in interpreting biomonitoring concentrations, better attribute exposures to likely sources, and strengthen the scientific basis for identifying the most important exposure pathways for risk management and public health action.
Which EPA office or program is running this opportunity?
The opportunity is run by the EPA's Center for Public Health and Environmental Assessment (CPHEA) in coordination with the Agency's Safe and Healthy Communities National Research Program.
What type of grant program is this described as?
It is described as a discretionary grant program focused on environmental research and public health exposure science.
How many awards does EPA expect to make, and what is the maximum award amount?
The award ceiling is $250,000 per award, and there is an expectation of two awards.
When was the opportunity created and when did it originally close?
The opportunity was created on July 7, 2021, and it originally closed on August 23, 2021.
Where should applicants look for submission requirements and exact due dates?
The notice indicates that applicants should consult the official announcement, including Section IV, for submission requirements, methods, and the exact due dates.
Who is eligible to apply based on the notice?
Eligibility is listed broadly as "Others," with specific eligible applicant types to be clarified in the announcement's eligibility section.
What is the main research emphasis of projects funded under this opportunity?
The emphasis is on collecting multimedia measurements that are relevant to PFAS exposure pathways and pairing those measurements with existing PFAS biomonitoring data from cohort participants.
What problem is this opportunity trying to address in PFAS exposure science?
PFAS involve many compounds, many potential sources, and multiple exposure routes that can vary by geography, behaviors, infrastructure, and product use. The opportunity aims to strengthen exposure measurement methods and make studies more comparable so researchers can more confidently identify dominant pathways and explain differences in human PFAS body burdens.
What kinds of outcomes or insights are these projects expected to produce?
Projects are intended to produce datasets that help explain where PFAS exposures are coming from and which pathways contribute most to PFAS measured in the body, improving interpretation and supporting stronger conclusions across cohorts and locations.
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